Mark D. Van Poppel, MD | CNSA Physician | Neurosurgeon & Spine Specialist in Charlotte NC

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Mark D. Van Poppel, MD

Special Interests

  • Adult and Pediatric Brain Tumors
  • Adult and Pediatric Neurosurgery
  • Adult and Pediatric Surgical Management of Epilepsy
  • Adult and Pediatric Stereoelectroencephalography (SEEG)
  • Adult and Pediatric Laser Interstitial Thermal Therapy (LITT)
  • Endoscopic Cranial Surgery
  • Neurotrauma


Providing care as a neurosurgeon at Carolina NeuroSurgery & Spine Associates for over 9 years, Dr. Van Poppel’s clinical interests include adult and pediatric epilepsy management, brain tumor treatment, and endoscopic cranial surgery. He is also the clinic expert in epilepsy for the practice, providing expertise in epileptic related care management and surgical intervention.

He is the only physician in the Charlotte region to perform Stereoelectroencephalography (SEEG), treating both adult and pediatric patients who are diagnosed with epilepsy.

Dr. Van Poppel’s expertise and positive reputation has led him to hold many leadership roles in and outside of the medical practice. He values working for Carolina NeuroSurgery & Spine Associates because the organization is strategically structured in a way to care for all patients with any neurosurgical needs, no matter their age or condition.

     “Our unique peer to peer collaboration within the field of neurosurgery creates a multidisciplinary approach to patient care. I believe that this is the best model for a practice to care for the patient and achieve an optimal outcome. The collegial nature of our environment ensures I always have a trusted colleague to consult with in order to discuss each unique patient, no matter their diagnosis or complexity.

     I have trained and studied at other nationally recognized medical centers and academic institutions and feel that working at Carolina NeuroSurgery & Spine Associates affords me the ability to care for patients to my fullest potential. Whether a patient shows up in a hospital emergency room or in our office, we are ready and prepared to act with a sense of urgency, creating a unique road map to meet their immediate and long term care needs,” says Dr. Van Poppel.

From a young age, Dr. Van Poppel took an interest in biology and human anatomy. Dr. Van Poppel started his undergrad as a biology research major. During college, he did a work study program in pathology. This was a pivotal educational experience that led him to pursue medical school. Exploring various surgical specialties, it became quite obvious to him that neurosurgery was the right fit. The field of neurosurgery presents daily challenges that when addressed, provide life-changing results.

     “For me, I don’t need coffee to start my day. It energizes me to wake up and solve new and unique challenges. My innate drive and intrigue for the field of neurosurgery is what propels me forward to give my all for my patients and their families who look to us to help them achieve a better quality of life. It is that same momentum that has kept me finding each new day fulfilling as a neurosurgeon,” says Dr. Van Poppel.

Starting out as a neurosurgeon over 9 years ago, Dr. Van Poppel initially preferred his operating room days. As it was the complexity of neurosurgical intervention that solidified his career path. But throughout his career, he has grown to enjoy his clinic days and time spent with patients almost as much as the operating room.

Dr. Van Poppel is originally from South Bend, IN. He is married and together they parent two grade school aged children, a son and daughter. An interesting fact about Dr. Van Poppel is that he met his wife, who is also a physician, while they were both attending medical school at Indiana University. She also serves patients in the Carolina region and is board certified in child neurology, neurodiagnostics and epilepsy.

     “Being married to someone who understands my passion for patient care means that she can personally and professionally relate to my internal drive to serve patients better today than the day before. We serve patients in the same community, so it is truly a family effort,” says Dr. Van Poppel.

While Dr. Van Poppel treats both adult and pediatric patients, being a parent himself enhances his ability to relate when interacting with pediatric patients and their families. Dr. Van Poppel and his care team understand that helping to navigate families throughout their child’s unique and sensitive care needs is an honor.

Outside of work, Dr. Van Poppel values spending time with his family doing things they enjoy such as water sports. Dr. Van Poppel is a die-hard hockey fan and says “hockey is my baseball,” meaning he could watch hockey for hours as if time hasn't passed. If you are a patient of his, feel free to ask him more about his favorite team!


  • Fellowship
    Pediatric Neurosurgery, Le Bonheur Children’s Hospital/St. Jude Children’s Research Hospital
  • Residency & Internship
    University of Tennessee and Semmes-Murphey Clinic
  • Medical School
    Indiana University School of Medicine
  • Master of Science in Anatomy and Cellular Physiology
    Indiana University
  • Master of Science in Biology
    Purdue University

Affiliations & Memberships

  • Board Certified by the American Board of Pediatric Neurological Surgery (ABPNS)
  • Member of the American Society of Pediatric Neurosurgeons (ASPN)
  • Member of the American Association of Neurosurgery (AANS)
    • Certified in Pediatric Neurosurgery Section (AANS/CNS)
  • Medical Director of Neurotrauma, Atrium Health Neurosciences Institute
  • Vice Chair, Carolinas Medical Center Department of Neurosurgery
  • Assistant Program Director, Atrium Health Carolinas Medical Center Neurosurgical Residency Program

Dr. Van Poppel's Care Team

Lauren Colombo, PA-C
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